Tru Niagen®
Tru Niagen®
Powered by Niagen®, this clinical-strength serving of our patented nicotinamide riboside (NR) is clinically proven to increase NAD+ levels, helping your cells produce more energy and support better aging.
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Tru Niagen®
Truniagen has been a game changer in improving my health. Mitochondrial and cellular health in general are front and center in the fight for renewed vitality and longevity. That's what I feel truniagen has done for me. By improving my mitochondrial health I feel stronger, more focused and energized from day to day. I believe it has given me support in losing weight and is a long time part of my personal care regimen.
A naturally occurringsupernutrient for your cells.
NAD+ is a crucial coenzyme that powers your cells. converting nutrients into energy while activating key enzymes for DNA repair and cellular resilience. After decades of research, scientists now recognize NAD+ as fundamental to maintaining healthy cellular function throughout your body.
Function
- Niagen®, our patented nicotinamide riboside, is the research-grade NAD+ precursor trusted by 65% of clinical studies.²
- As one of the most well-researched NAD+ supplements available, Niagen® increases NAD+ more efficiently than other NAD+ precursors and supplements.
- Our clinical-strength 1,000mg daily serving delivers proven NAD+ increases up to 150% to support optimal cellular function, energy production, and cellular repair.
- Formerly exclusive to physicians and professional athletes, this potent formula supports cellular health, brain function, muscle health, and heart health†.
- Supports healthy aging and enhanced cellular resilience for those with active lifestyles, age-related concerns, and additional lifestyle stressors.
- Niagen is routinely used in published peer-reviewed studies. When researchers demand results, they choose our proven formula.
Age better with Tru Niagen.
Clinically proven to increase NAD+ by up to 150% in 3 weeks
Patented high-absorption Niagen delivers proven, reliable results unlike NAD+ itself, NMN, and experimental liposomal supplements.
The only FDA reviewed and GRAS certified NR in the world.
Clean ingredients and rigorous third-party testing you can trust.
Whole-body benefits
From your daily routine to your biggest goals, Tru Niagen powers your cellular health, helping you thrive.
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Healthy Aging
Helps target hallmarks of aging
Replenish NAD+ daily to keep your cells energized, supported during repair, and resilient
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Brain Health
Supports brain health
Support your hardworking brain cells with increased NAD+.
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Heart Health
Supports heart health†
Supports cellular energy that your heart cells need.
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Muscle Health
Cellular performance and repair
Help fuel your muscle cells to support recovery and repair.
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Cellular Health
Cellular energy and DNA repair
Support your 37.2 trillion cells by supporting cellular energy, metabolism, and repair.
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Lifestyle Stress Management*‡
Mitigate the effect of stressors
Daily stressors can deplete NAD+, which can accelerate aging. Replenish NAD+ to support your health.
Backed by gold standard science, quality, and safety
Backed by gold standard science, quality, and safety
Efficacy backed by peer-reviewed published research
Niagen® is supported by 35+ clinical studies demonstrating its safety and efficacy. These human studies form the foundation of our scientific evidence. Over 65% of registered ongoing or completed nicotinamide riboside trials use Niagen®.²Partnership with 300+ institutions: We partner with top institutions like Mayo Clinic, National Institute on Aging, Harvard, and Cambridge.Backed by independent research: Over 90% of peer-reviewed, published Niagen® studies are investigator-driven and third-party funded.View studies and publications
Efficacy backed by peer-reviewed published research
Niagen® is supported by 35+ clinical studies demonstrating its safety and efficacy. These human studies form the foundation of our scientific evidence. Over 65% of registered ongoing or completed nicotinamide riboside trials use Niagen®.²Partnership with 300+ institutions: We partner with top institutions like Mayo Clinic, National Institute on Aging, Harvard, and Cambridge.Backed by independent research: Over 90% of peer-reviewed, published Niagen® studies are investigator-driven and third-party funded.View studies and publications
Third-party verified for safety and quality
We employ rigorous quality testing to support your health. Our science-backed supplements are routinely assessed by third-party testers for quality, safety, and potency.
NSF Certified for Sport®
NSF's Certified for Sporte is the only third-party certification recognized by United States Anti-Doping Agency (USADA), Major League Baseball (MLB), and the National Hockey League (NHL)
To earn this, supplements must meet strict quality standards, contain no unsafe contaminants, and be free of 270+ banned substances. Both Tru Niagen Stick Packs and Tru Niagen Pro are made in NSF- audited, GMP-certified facilities, with every batch verified for safety and transparency on NSF's Certified for Sport@ website.
Verified for potency and quality
Each batch of Tru Niagen@ is verified by leading third-party labs to ensure purity and potency. Built on quality, safety, and transparency, every product meets the highest standards.
Visit our Quality page to access your bottle's certificate of analysis.
"In the supplement industry, where claims oftenoutpace evidence,scientific rigor is paramount. This is why l'm particularly impressed by thework being done at Niagen Bioscience.
Roger Kornberg
Nobel Prize WinnerProfessor of Structural Biology at Stanford
Backed by 25 years of research & innovation
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Human Clinical Studies
Backed by peer-reviewed published studies.
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Nobel Prize Winners
Backed by a Scientific Advisory Board of world-leading researchers.
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Patents
Backed by innovation gold standards in the supplement space.
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Published Scientific Studies
NR is well-researched in published preclinical and clinical studies.
About Tru Niagen
Developed by Niagen Bioscience, formerly ChromaDex, a pioneer in NAD+ and healthy-ageing research, Tru Niagen® is the number one NAD+ brand in the United States.³
Helping people around the world transform the way they age, Tru Niagen is clinically proven to increase NAD+ levels and help sustain them over time. It’s powered by our patented form of nicotinamide riboside, Niagen®, the most well-researched, quality-tested, efficient NAD+ precursor available.
We set the gold standard in scientific rigor, safety, quality, and transparency. Backed by two Nobel Prize winners, 35+ human clinical studies, and 400+ published scientific studies, and has been accepted by the world’s most rigorous regulatory bodies.
We want to get the most out of every moment. Our purpose is to invigorate life, even through challenging times.
We want to get the most out of every moment. Our purpose is to invigorate life, even through challenging times.
A legacy of innovation and discovery
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1999
A vision is born
ChromaDex is founded with a bold mission: to bring cutting-edge science to the world. Collaborating with top universities and institutions, we set the stage for life-changing health innovations.
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2005
Science takes center stage
We begin licensing groundbreaking ingredient technologies. This pivotal moment drives our ambition to unlock new possibilities in human health through science.
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2013
Introducing Niagen
ChromaDex makes waves with Niagen, a patented form of Nicotinamide Riboside (NR). This revolutionary discovery redefines cellular health and aging, bringing us closer to healthier lives.
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2016
The Launch of Tru Niagen
With Tru Niagen, our vision becomes reality. Consumers around the world can now support their cellular health through this innovative product, marking a new era for ChromaDex.
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2020
Global expansion
Tru Niagen expands internationally, cementing ChromaDex as a leader in health and wellness. Our evidence-based approach earns global recognition and trust.
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Today
Global expansion
Tru Niagen goes global, establishing ChromaDex as a health and wellness leader worldwide. Our science-backed approach continues to build trust across international markets.
Setting the gold standard in the supplement industry since 1999.
Niagen Bioscience, formerly ChromaDex, represents 25 years of world-leading scientific innovation and excellence. Tru Niagen is backed by Nobel prize-winning scientists, 35+ published peer-reviewed human clinical studies and 400+ published studies.
Our dedication to scientific research
We value and encourage strong scientific rigor and evidence behind our claims. We have a dedicated state-of-the-art research and development facility in Longmont, Colorado. Our science is global with more than 275+ research collaborations through theChromaDex External Research Program (CERP), a division of Niagen Bioscience.
Quality. Science. Integrity.
Since our founding in 1999, we've built our company on an uncompromising foundation of quality. Our ChromaDex External Research Program (CERP), launched in 2013, has supplied quality-tested, trusted Niagen® NR to 200+ leading universities and scientific institutions worldwide.
As pioneers in commercializing nicotinamide riboside (NR) as Niagen® (nicotinamide riboside chloride, or NRCl), we've set new benchmarks for scientific rigor and manufacturing excellence. Our cutting-edge research and development facility in Longmont, CO, serves as the heart of our operations—where rigorous science meets uncompromising quality standards.
Every batch. Every capsule. Every breakthrough. Built on decades of scientific excellence.
Committed to scientific rigor in all we do
We prioritize strong scientific rigor and evidence above all. To date, we’ve participated in over 275 global scientific research collaborations through theChromaDex External Research Program (CERP®), a division of Niagen Bioscience.
As of today, 40 peer-reviewed, published human clinical studies have demonstrated the safety and efficacy of Niagen in elevating NAD+.
Every day, we continue to pioneer research on the benefits of our products to help combat the effects of aging and improve health and well-being across the globe.
Made in the U.S.A. with internationally sourced materials
Tru Niagen is blended, encapsulated, and bottled in the United States using globally sourced components that meet our exacting standards. Our active ingredient Niagen® comes from trusted domestic manufacturing partners, while final product assembly happens exclusively at U.S. facilities.
Every batch undergoes at least 19 comprehensive quality tests—13 for our food-grade Niagen® ingredient and an additional 6 for the finished Tru Niagen product—all conducted through our ISO-accredited laboratory in Longmont, Colorado, and verified by third-party U.S.-based testing partners NSF and Alkemist.
Frequently Asked Questions
What is NAD+ and how does it work?
What is NAD+ and how does it work?
NAD+ (Nicotinamide Adenine Dinucleotide) is a crucial coenzyme found in every cell of your body that powers hundreds of metabolic processes. It serves as a key player in cellular energy production, DNA repair, and cellular communication. NAD+ works by transferring electrons during cellular metabolism, enabling your cells to convert nutrients into energy and supporting essential functions that keep your body running optimally.
What are the potential benefits of taking NAD+ supplements?
What are the potential benefits of taking NAD+ supplements?
NAD+ levels naturally decline from birth, accelerating around age 30, and dropping by up to 65% by age 70. Environmental and lifestyle stressors also diminish NAD+ levels, as do immune and health challenges. Taking a clinically proven supplement like Tru Niagen helps maintain your NAD+ baseline levels with daily use—to keep your body running smoothly as you age.
What is the difference between Tru Niagen and other NAD brands on the market?
What is the difference between Tru Niagen and other NAD brands on the market?
Tru Niagen is a superior choice compared to other NAD supplements because it contains Niagen®, our patented nicotinamide riboside (NR), a more bioavailable precursor to NAD+. Niagen® NR is backed by 35+ human clinical studies, and crosses cell membranes easily and is more efficiently converted into NAD+ inside cells, effectively boosting NAD+ levels.
This enhances energy metabolism, supports cellular repair, and promotes healthy aging, making Tru Niagen a more reliable, high-quality, pure, and potent option for raising NAD+ compared to other supplements. Tru Niagen® is clinically proven to increase NAD+ levels by over 50% with 300mg daily and by up to 150% with 1000mg daily and is backed by third-party quality-testing from NSF Certified for Sport and Alkemist Labs.
How quickly can l expect to see results from taking Tru Niagen?
How quickly can l expect to see results from taking Tru Niagen?
Most people report noticing improvements in cellular energy and overall wellbeing within 2-4 weeks of consistent daily use. However, the cellular health benefits of increased NAD+ levels begin immediately, even before you feel noticeable changes.
Clinical studies show that Tru Niagen begins elevating NAD+ levels within hours of taking your first dose, with significant increases observed within 2 weeks of daily supplementation. For optimal results, we recommend taking Tru Niagen consistently as part of your daily routine.
Is Tru Niagen safe, and are there any side effects?
Is Tru Niagen safe, and are there any side effects?
Tru Niagen has been rigorously tested for safety and is well-tolerated. Our proprietary key ingredient Niagen® has successfully completed multiple FDA safety reviews and is manufactured in cGMP-certified facilities in the USA.
Niagen is supported by 35+ clinical studies demonstrating its safety and efficacy. These human studies form the foundation of our scientific evidence. Over 65% of registered ongoing or completed nicotinamide riboside trials use Niagen.² Niagen is also backed by independent research, with over 90% of Niagen studies being investigator-driven and third-party funded.
In clinical studies, participants reported minimal to no side effects when taking the recommended dosage up to 2,000mg per day. Some individuals may experience mild and temporary effects that typically resolve quickly. As with any supplement, we recommend consulting with your healthcare provider before starting Tru Niagen, especially if you have existing health conditions or take medications.
How does the 1000mg Pro serving compare to other available servings like 300mg?
How does the 1000mg Pro serving compare to other available servings like 300mg?
Tru Niagen Pro 1000mg is clinical strength, and the serving most often used in clinical studies. This product was formerly exclusive to physicians and pro athletes, and is now available to consumers who are seeking a higher serving of Niagen that is clinically proven to increase NAD+ levels by up to 150%.
Depending on your lifestyle and your age, we recommend working closely with your healthcare provider to determine the best serving size for your specific needs. You can also take our Product Quiz to see what serving might be right for you.
1000mg of Niagen is the most extensively researched daily dose, and the serving preferred in human clinical trials. Based on studies, Tru Niagen is safe for daily use at up to 2000mg.
Customers Reviews
Elena
⭐⭐⭐⭐⭐ Verified Purchase
Tru Niagen review I’ve been using Tru Niagen for a while, and I’ve noticed a steady improvement in my energy levels and focus throughout the day. It’s easy to take and doesn’t cause any side effects for me. I can’t say it’s a dramatic change, but overall I do feel healthier and more balanced since starting it.
Shopitlikeitshot
⭐⭐⭐⭐⭐ Verified Purchase
More focused and happy I’ve been taking 1000 consistently lately and what I’ve noticed is that my cognitive function is improving. I usually have a lot of brain fog in the mornings sometimes throughout the day this is helped improve my brain fog, my focus, and taking in information. I’ve also noticed I feel more happy and a lot more energetic. I can definitely tell a difference in my mood and feel more stable. It’s almost like being an anti-depressant.
Bobbyo
⭐⭐⭐⭐⭐ Verified Purchase
NAD suppliment Only my second bottle and I have so much energy. My thinking is clearer and my mood is better.
I love it!
⭐⭐⭐⭐⭐ Verified Purchase
Title: Best Value NAD Supplement – Effective and Worth Every Penny I normally take 1000 mg of NAD daily, but I also started using this TRU NIAGEN 300 mg version because the price is much better. Instead of taking 1000 mg all at once, I split the dosage – sometimes twice a day, sometimes three times a day – one capsule each time. Surprisingly, the effect feels even better this way, and it saves a lot of money. The quality is very high, and the results are clear: more energy, better focus, improved sleep, and even my skin looks brighter and younger, almost like turning back 10–20 years. I have tried many different NAD products, but this one is the most stable and effective. Some people say it is expensive, but after comparing many brands, I believe it is not expensive at all considering the results. The price here is even better than directly buying from the manufacturer, which is why I always order two large bottles (90 capsules each) at a time. I highly recommend this product to anyone who truly wants to feel younger and stronger. I will continue to use it and to leave honest reviews, because this product is worth every cent.